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Related Experiment Videos

Proteinuria--what value is the dipstick?

N A Harrison1, D J Rainford, G A White

  • 1Renal Unit, Princess Mary's Royal Air Force Hospital, Aylesbury.

British Journal of Urology
|February 1, 1989
PubMed
Summary
This summary is machine-generated.

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The urinary dipstick test accurately identifies significant proteinuria (≥150 mg/24 h) in 88% of cases. Repeat testing can clarify borderline results, aiding in renal disease detection.

Area of Science:

  • Nephrology
  • Clinical Chemistry

Background:

  • Proteinuria assessment is crucial for diagnosing renal disease.
  • Urinary dipstick testing offers a rapid screening method for proteinuria.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of the urinary dipstick test for proteinuria.
  • To correlate dipstick results with quantitative laboratory measurements of protein and albumin.

Main Methods:

  • Prospective study involving 94 patients (100 admissions) at a Renal Unit.
  • Collection of two 24-hour urine samples per patient.
  • Simultaneous dipstick testing and laboratory assay of urine aliquots at three daily times.

Main Results:

  • A dipstick result of + or more correlated with abnormal proteinuria (≥150 mg/24 h) in 88% of cases.

Related Experiment Videos

  • Trace dipstick results were equivocal, requiring further differentiation by repeat testing.
  • A negative dipstick result accurately indicated normality in all but 5% of cases.

    • Conclusions:

    • The urinary dipstick is a reliable initial screening tool for proteinuria.
    • Repeat dipstick testing can improve accuracy for borderline results.
    • Assessing mid-morning urine samples is recommended for detecting isolated orthostatic proteinuria.