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Interspecific variations of cerebral endothelial cholinesterases in rodents and carnivores
J Trancard1, I S Delamanche, G Ruiz
1Centre de Recherche Delalande, Rueil-Malmaison, France.
Brain Research
|January 9, 1989
Abstract:
The cholinesterase equipment of cerebral microvessels was studied in some rodents and carnivores using the Koelle-Friedenwald histochemical method with 3 artificial substrates and specific inhibitors for butyrylcholinesterase or acetylcholinesterase. Our observations reveal a great heterogeneity in cholinesterase types and their distribution in each of the different species studied. Only in the rat, butyrylcholinesterase appears to be a marker for the microvessels provided with a blood-brain barrier.