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Effects of preoptic area lesions on muramyl dipeptide-induced sleep and fever
S Shoham1, C M Blatteis, J M Krueger
1Department of Physiology and Biophysics, University of Tennessee, Memphis 38163.
Brain Research
|January 9, 1989
Abstract:
Lesions of the preoptic area of rabbits caused hyperthermia, although they did not alter sleep-coupled changes in brain temperature, and reduced slow-wave sleep, rapid eye movement sleep, and amplitudes of electroencephalographic slow waves during slow wave sleep. The direction and magnitude of the muramyl dipeptide-induced responses were similar before and after the lesions, although the baseline values upon which the changes were superimposed had shifted.