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Updated: Mar 23, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Unique nonstructural dysfunction of the omnicarbon valve: case report
Soki Kurumisawa1, Yuichiro Kaminishi1, Arata Muraoka1
1Division of Cardiovascular Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotuske, Tochigi, 329-0498, Japan.
Background:
Pannus formation may disturb the leaflet movement of the prosthetic valve.
Case Presentation:
A 61-year-old woman presented with exertional dyspnea. She had undergone mitral valve replacement with a bioprosthetic valve 31 years ago, which was replaced with a tilting disc valve 22 years ago. The present laboratory findings revealed hemolytic anemia. Echocardiography showed an increased mean pressure gradient through the mitral valve and moderate to severe regurgitation around the minor orifice of the tilting disc valve. She therefore underwent a third operation. Pannus formation was found on the prosthetic valve ring, but it did not obliterate the prosthetic valve orifice. After removing the valve, the posterior wall of the left ventricle was seen to be associated with thickened endocardium. A bileaflet valve was implanted. Postoperative echocardiography showed that the implanted valve functioned well.
Conclusions:
Nonstructural dysfunction of the mechanical heart valve might occur long after operation. These changes are particularly observed with a tilting disc valve.
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