Related Experiment Video

Updated: Mar 23, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

10.4K

A rare cause of cerebral venous thrombosis: cryptococcal meningoencephalitis

Songul Senadim1, Sezin Alpaydin Baslo2, Betül Tekin Güveli2

  • 1Department of Neurology, Bakirkoy Research and Training Hospital for Psychiatry, Neurology, Neurosurgery, Istanbul, Turkey. songulsenadim@gmail.com.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|March 31, 2016
PubMed

Insights

Cryptococcal meningoencephalitis (CM) is a rare central nervous system infection. This report details an immunocompetent patient with CM and cerebral venous thrombosis, highlighting atypical symptoms in non-endemic areas.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Mycology

Background:

  • Cryptococcal meningoencephalitis (CM) is a severe CNS infection primarily affecting immunocompromised individuals.
  • Cryptococcus neoformans is the causative agent, with HIV infection being a major risk factor.
  • CM is uncommon in immunocompetent hosts, making such cases noteworthy.

Purpose of the Study:

  • To report a rare case of CM in an immunocompetent patient.
  • To describe atypical clinical presentations and a rare complication (cerebral venous thrombosis).
  • To contribute to understanding CM in non-endemic regions.

Main Methods:

  • Case report of a single patient.
  • Clinical presentation and diagnostic workup described.
  • Literature review for similar cases.

Main Results:

  • An immunocompetent patient presented with acute onset of atypical symptoms.
  • Cerebral venous sinus thrombosis was identified as a complication of CM.
  • The patient was from a non-endemic area for cryptococcosis.

Conclusions:

  • CM can occur in immunocompetent individuals, even in non-endemic areas.
  • Cerebral venous thrombosis is a rare but possible complication of CM.
  • Atypical presentations necessitate a high index of suspicion for CM.
Keywords:
Cerebral venous thrombosisCryptococcal meningoencephalitisImmunocompetent patientInfectious diseaseTreatment

More Related Videos

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

20.6K

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
30
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
8
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
666
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
11
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
432
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
459