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Basosquamous papilloma. A benign epithelial skin tumor with multiple cytogenetic clones
1Department of Clinical Genetics, Lund University Hospital, Lund, Sweden.
Cancer Genetics and Cytogenetics
|February 1, 1989
Abstract:
Cytogenetic analysis of short-term cultures from a basosquamous papilloma revealed the following mosaic karyotype: 46,XX,t(2;5)(q31;q31),t(8;15)(p21;q21)/46,XX,t(7;17)(p13;p13)/47,XX, t(3;20)(q12;p13),+7/46,XX,t(1:12)(p12;q13). The finding of four abnormal, cytogenetically unrelated clones suggests a multicellular origin of this benign skin tumor. None of the structural rearrangements encountered have previously been associated with neoplasia.