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Updated: Mar 23, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
DOUBLE-BUNDLE ANATOMICAL RECONSTRUCTION OF THE ANTERIOR CRUCIATE LIGAMENT: A PROSPECTIVE STUDY WITH TWO-YEAR
Julio Cesar Gali1, Maurício Sante Bettio Mod2, Hélio Massahiro Mimura2
1PhD in Orthopedics and Traumatology from the USP School of Medicine. Attending Physician at Apex Orthopedics and Traumatology and at the Unimed Hospital, Sorocaba.
Objective:
To prospectively evaluate the results from double-bundle reconstruction of the anterior cruciate ligament, among patients at our clinic, by means of the 2000 protocol of the International Knee Documentation Committee (IKDC).
Study Design:
Case series; level of evidence IV.
Methods:
Fifty-eight patients who underwent anatomical reconstruction of the anterior cruciate ligament using an autologous flexor tendon graft by means of the double-bundle technique were evaluated in accordance with the IKDC 2000 protocol. The patients' ages ranged from 17 to 58 years, with a mean of 35.2 years. The follow-up ranged from 24 to 37 months (mean of 28.9 months).
Results:
Postoperatively, 89.65% of the pivot-shift test findings were negative. In the final evaluation, 44 (75.86%) of the patients' knees were graded as normal, 13 (22.41%) as nearly normal and one (1.72 %) as abnormal.
Conclusion:
The technique used was effective in promoting restoration of joint stability, without compromising mobility.

