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Updated: Mar 23, 2026
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Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
Published on: June 15, 2012
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Efficient Purification and Release of Circulating Tumor Cells by Synergistic Effect of Biomarker and SiO2
Qinqin Huang1, Bo Cai1, Bolei Chen2
1Key Laboratory of Artificial Micro- and Nano-Structures of Ministry of Education School of Physics and Technology, Wuhan University, Wuhan, 430072, Hubei, P. R. China.
Advanced Healthcare Materials
|March 31, 2016
Abstract:
Microfluidics-based circulating tumor cell (CTC) isolation is achieved by using gelatin-coated silica microbeads conjugated to CTC-specific antibodies. Bead-binding selectively enlarges target cell size, providing efficient high-purity capture. CTCs captured can be further released non-invasively. This stratagem enables high-performance CTC isolation for subsequent studies.
