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Updated: Mar 23, 2026
Characterization of Human Monocyte Subsets by Whole Blood Flow Cytometry Analysis
Published on: October 17, 2018
Monocyte subsets and monocyte-platelet aggregates: implications in predicting septic mortality among surgical
Qin Wu1, Jianan Ren1, Dong Hu1
1a Department of General Surgery , Jinling Hospital, Medical School of Nanjing University , Nanjing , China.
Background:
Monocyte subsets and monocyte-platelet aggregates (MPAs) play important roles in inflammation.
Aim:
To evaluate the association between the three human monocyte subsets and their contributions to MPAs and mortality among septic patients.
Methods:
Consecutive septic patients were enrolled in. Age- and gender-matched nonseptic patients were recruited as control patients. Monocyte subsets and monocyte-platelet aggregates were determined by flow cytometric analysis.
Results:
Elevated percentage of MPAs (MPAs%) was associated with an increased risk of mortality.
Conclusions:
This study demonstrated increased MPAs% enables the identification of a group of septic patients at high risk of death.
