Related Experiment Video
Updated: Mar 23, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Opportunities for the Cardiovascular Community in the Precision Medicine Initiative
Svati H Shah1, Donna Arnett2, Steven R Houser2
1From Division of Cardiology, Department of Medicine, Duke University, Durham, NC (S.H.S., G.S.G.); Duke Molecular Physiology Institute, Duke University, Durham, NC (S.H.S.); School of Public Health, University of Alabama at Birmingham, Birmingham, AL (D.A.); Division of Cardiology, Department of Medicine, Temple University School of Medicine, Philadelphia, PA (S.R.H.); Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA (S.R.H.); Duke Center for Personalized Medicine, Department of Medicine, Duke University, Durham, NC (G.S.G.); Division of Cardiology, Department of Medicine, Brigham and Women's Hospital, Boston, MA (C.M., J.L.); Division of Cardiology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada (S.M.); and Lillehei Heart Institute, Division of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN (J.L.H.). jlhall@umn.edu svati.shah@duke.edu.
Abstract:
The Precision Medicine Initiative recently announced by President Barack Obama seeks to move the field of precision medicine more rapidly into clinical care. Precision medicine revolves around the concept of integrating individual-level data including genomics, biomarkers, lifestyle and other environmental factors, wearable device physiological data, and information from electronic health records to ultimately provide better clinical care to individual patients. The Precision Medicine Initiative as currently structured will primarily fund efforts in cancer genomics with longer-term goals of advancing precision medicine to all areas of health, and will be supported through creation of a 1 million person cohort study across the United States. This focused effort on precision medicine provides scientists, clinicians, and patients within the cardiovascular community an opportunity to work together boldly to advance clinical care; the community needs to be aware and engaged in the process as it progresses. This article provides a framework for potential involvement of the cardiovascular community in the Precision Medicine Initiative, while highlighting significant challenges for its successful implementation.
Related Concept Videos
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Pharmacogenomics: Identification of New Drug Targets
Coronary Artery Disease IV: Preventive Measures
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine
Cardiomyopathy V: Interprofessional Care

