Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hydrostatic Pressure Force on a Curved Surface01:04

Hydrostatic Pressure Force on a Curved Surface

2.7K
Hydrostatic pressure on curved surfaces is a fundamental concept in fluid mechanics with broad applications in the civil engineering field. When fluid is in contact with a curved surface, as in a reservoir, dam, or storage tank, it exerts pressure that varies in magnitude and direction along the curved surface. To assess the total hydrostatic force exerted by the fluid on a curved structure, engineers typically isolate the fluid volume adjacent to the surface and analyze the forces acting on...
2.7K
Bending of Curved Members - Neutral Surface01:16

Bending of Curved Members - Neutral Surface

589
In curved beams, unlike straight beams, the stress distribution across the cross-section is not uniform due to the beam's curvature. This non-uniformity arises because the neutral axis, where stress is zero, does not align with the centroid of the section. In a curved beam, the strain varies along the section as a function of the distance from the neutral axis.
Consider the curved member described in the previous lesson. According to Hooke's law, which relates stress to strain within the...
589
Molecular Geometry and Dipole Moments02:36

Molecular Geometry and Dipole Moments

20.0K
The VSEPR theory can be used to determine the electron pair geometries and molecular structures as follows:
20.0K
Surface Tension of Fluid01:22

Surface Tension of Fluid

1.9K
Surface tension is a fundamental property of fluids, occurring at the boundary between a liquid and a gas or between two immiscible liquids. This phenomenon arises from the cohesive forces between molecules at the fluid's surface, creating an effect similar to a stretched elastic membrane. Inside each fluid, molecules are equally attracted in all directions by neighboring molecules, but surface molecules experience a net inward force, resulting in surface tension.
Surface tension varies...
1.9K
Mechanisms of Membrane-bending01:15

Mechanisms of Membrane-bending

3.7K
The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
3.7K
Dynamics of Circular Motion01:30

Dynamics of Circular Motion

25.9K
An object undergoing circular motion, like a race car, is accelerating because it is changing the direction of its velocity. This centrally directed acceleration is called centripetal acceleration. This acceleration acts along the radius of the curved path (thus is also referred to as radial acceleration).
Any acceleration must be produced by some force. Therefore, any force or combination of forces can cause centripetal acceleration. A few examples include the tension in the rope on a...
25.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hierarchical assembly is more robust than egalitarian assembly in synthetic capsids.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Interdisciplinary Research in Artificial Intelligence: Challenges and Opportunities.

Frontiers in big data·2021
Same author

Capping protein is dispensable for polarized actin network growth and actin-based motility.

The Journal of biological chemistry·2020
Same author

Myosin 1b is an actin depolymerase.

Nature communications·2019
Same author

Actin shells control buckling and wrinkling of biomembranes.

Soft matter·2019
Same author

Morphology formation in binary mixtures upon gradual destabilisation.

Soft matter·2019
Same journal

Heterogeneous binding of SARS-CoV2 fusion peptide on complex cellular membranes enhances its fusogenicity.

Biophysical journal·2026
Same journal

Tau protein differentially affects Piezo1 and Kir2.1 channels in brain capillary endothelial cells.

Biophysical journal·2026
Same journal

Emergent Intercellular Junction Stability during Cyclic Tissue Loading.

Biophysical journal·2026
Same journal

Enhanced-Sampling Simulations Reveal Distinct Intermediates in SARS-CoV-2 FSE Pseudoknot Interconversion.

Biophysical journal·2026
Same journal

Structure-based simulations of the full Flock House virus capsid reveal pathways and energetics of an infection-critical peptide externalization event.

Biophysical journal·2026
Same journal

Quantifying the Peripheral Surface Information Entropy from Conformational Ensembles of Globular Protein-Peptide Complexes.

Biophysical journal·2026
See all related articles

Related Experiment Video

Updated: Mar 23, 2026

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs
05:00

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs

Published on: August 9, 2024

2.1K

A Method for Molecular Dynamics on Curved Surfaces.

Stefan Paquay1, Remy Kusters1

  • 1Department of Applied Physics, Eindhoven University of Technology, Eindhoven, the Netherlands.

Biophysical Journal
|March 31, 2016
PubMed
Summary
This summary is machine-generated.

This study introduces a molecular dynamics method for simulating particle interactions on curved surfaces, crucial for understanding biological processes like protein diffusion and virus self-assembly.

More Related Videos

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package
06:37

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package

Published on: September 17, 2021

5.2K
Probing C84-embedded Si Substrate Using Scanning Probe Microscopy and Molecular Dynamics
13:58

Probing C84-embedded Si Substrate Using Scanning Probe Microscopy and Molecular Dynamics

Published on: September 28, 2016

12.3K

Related Experiment Videos

Last Updated: Mar 23, 2026

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs
05:00

Author Spotlight: Streamlining Visual Dynamics to Simplify Molecular Dynamics Simulations Using Gromacs

Published on: August 9, 2024

2.1K
Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package
06:37

Analyzing Melts and Fluids from Ab Initio Molecular Dynamics Simulations with the UMD Package

Published on: September 17, 2021

5.2K
Probing C84-embedded Si Substrate Using Scanning Probe Microscopy and Molecular Dynamics
13:58

Probing C84-embedded Si Substrate Using Scanning Probe Microscopy and Molecular Dynamics

Published on: September 28, 2016

12.3K

Area of Science:

  • Computational physics
  • Biophysics
  • Materials science

Background:

  • Simulating particle dynamics on curved surfaces is vital for understanding biological processes.
  • Existing methods struggle to incorporate particle interactions, essential in crowded biological systems.
  • Diffusive transport on curved surfaces often focuses on solving the diffusion equation, limiting interaction modeling.

Purpose of the Study:

  • To develop a molecular dynamics simulation method for particles constrained to arbitrarily curved surfaces.
  • To enable the incorporation of particle interactions in simulations of diffusive transport on complex geometries.
  • To provide a versatile tool for studying biological and physical phenomena involving confined particle motion.

Main Methods:

  • Combining standard constraint algorithms with the velocity Verlet scheme for molecular dynamics simulations.
  • Utilizing Cartesian coordinates for simulations, allowing integration with existing computational tools.
  • Applying the developed schemes to the Langevin equation for simulating confined Brownian motion.

Main Results:

  • Successfully simulated molecular dynamics of particles on arbitrarily curved surfaces, including interactions.
  • Demonstrated confined Brownian motion applicable to various biological and physical problems.
  • Validated the method with simulations of protein lateral diffusion in curved membranes and virus capsid self-assembly.

Conclusions:

  • The developed method effectively simulates particle interactions on curved surfaces, overcoming limitations of previous approaches.
  • This technique offers a powerful new tool for investigating complex biological systems and physical phenomena.
  • The simulations provide insights into protein diffusion dynamics and viral structure formation.