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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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Association Between Periodontal Disease and Erectile Dysfunction: A Systematic Review
Sergio Varela Kellesarian1, Tammy Varela Kellesarian2, Vanessa Ros Malignaggi3
11 University of Rochester, Rochester, NY, USA.
American Journal of Men'S Health
|April 1, 2016
Summary
Erectile dysfunction (ED) and chronic periodontitis (CP) show a positive association. This systematic review suggests a link, recommending oral health evaluations for ED patients.
Area of Science:
- Oral Health
- Men's Health
- Systematic Reviews
Background:
- Limited studies explore the link between erectile dysfunction (ED) and chronic periodontitis (CP).
- Investigating this association is crucial for understanding potential shared risk factors and improving patient care.
Purpose of the Study:
- To systematically review and assess the association between chronic periodontitis (CP) and erectile dysfunction (ED).
- To answer the focused question: Is there a relationship between ED and CP?
Main Methods:
- Systematic literature search of indexed databases until December 2015.
- Included nine studies (seven cross-sectional, two RCTs) with participants aged 20-85.
- Excluded letters, commentaries, historical reviews, and experimental studies.
Main Results:
- All nine reviewed studies reported a positive relationship between CP and ED.
- Odds ratios in four studies ranged from 1.53 to 3.35, indicating increased odds of ED with CP.
- Participant numbers varied widely, from 53 to over 500,000.
Conclusions:
- A positive association between chronic periodontitis and erectile dysfunction is suggested by the current literature.
- Further well-designed controlled clinical trials are necessary to confirm this association.
- Physicians should consider referring patients with ED for oral health evaluations.
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