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Published on: October 11, 2011
Respiratory Rate During the First 24 Hours of Life in Healthy Term Infants
Lars Tveiten1, Lien My Diep2, Thomas Halvorsen3
1Department of Pediatrics, Innlandet Hospital Trust, Elverum, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway; and lars.tveiten@sykehuset-innlandet.no.
Insights
This study establishes normal respiratory rate (RR) ranges for healthy newborns in their first 24 hours. These findings provide a scientific basis for assessing infant breathing patterns and identifying potential health issues early.
Area of Science:
- Neonatal physiology
- Pediatric respiratory health
- Clinical reference ranges
Background:
- Abnormal respiratory rate (RR) is a critical indicator of neonatal disease.
- Establishing accurate reference ranges for RR in newborns is essential for early detection of health issues.
Purpose of the Study:
- To determine the reference range for respiratory rate (RR) in healthy, term infants during the initial 24 hours of life.
- Provide a scientifically validated tool for neonatal assessment.
Main Methods:
- Respiratory rate (RR) was measured in 953 healthy, term infants during sleep or quiet states at 2, 4, 8, 16, and 24 hours.
- Data collection involved stethoscope auscultation for 60 seconds.
- Maternal and birth data were sourced from medical records and the Medical Birth Registry of Norway.
Main Results:
- Median RR ranged from 42-46 breaths/minute, with 95th percentiles between 58-65 breaths/minute and fifth percentiles at 30-32 breaths/minute.
- Higher RR was observed in awake versus sleeping infants, after meconium staining, and in boys compared to girls.
- No significant difference in RR was found between infants born via vaginal or cesarean delivery.
Conclusions:
- The established RR percentiles offer a scientifically grounded method for evaluating newborn infants born at term.
- These reference ranges support clinical decision-making in neonatal care.
Background And Objective:
Abnormal respiratory rate (RR) is a key symptom of disease in the newborn. The aim of this study was to establish the reference range for RR during the first 24 hours of life in healthy infants born at term.
Methods:
Infants were included at the hospital postnatal ward when time permitted. During sleep or a defined quiet state, RR was counted at 2, 4, 8, 16, and 24 hours by placing the bell of a stethoscope in front of the nostrils and mouth for 60 seconds. Data on maternal health, pregnancies, and births were obtained from medical records and the Medical Birth Registry of Norway.
Results:
The study included 953 infants. Median RRs were 46 breaths/minute at 2 hours, thereafter 42 to 44 breaths/minute. The 95th percentile was 65 breaths/minute at 2 hours, thereafter 58 to 60 breaths/minute. The fifth percentile was 30 to 32 breaths/minute. Within these limits, the intraindividual variation was wide. The overall mean RR was 5.2 (95% confidence interval [CI], 4.7 to 5.7, P < .001) breaths/minute higher while awake than during sleep, 3.1 (95% CI, 1.5 to 4.8, P < .001) breaths/minute higher after heavy meconium staining of the amniotic fluid, and 1.6 (95% CI, 0.8 to 2.4, P < .001) breaths/minute higher in boys than girls. RR did not differ for infants born after vaginal versus cesarean deliveries.
Conclusions:
The RR percentiles established from this study allow for a scientifically based use of RR when assessing newborn infants born at term.
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