Related Experiment Video
Updated: Mar 23, 2026

Laser-Induced Chronic Ocular Hypertension Model on SD Rats
Published on: December 4, 2007
[Antioxidants in complex treatment of far-advanced open-angle glaucoma]
A N Gusev1, V N Krasnogorskaya1
1Amur State Medical Academy, Ministry of Health of the Russian Federation, 95 Gor'kogo St., Blagoveshchensk, Russian Federation, 675000.
Aim:
to evaluate treatment RESULTS in far-advanced glaucoma patients.
Material And Methods:
A total of 81 patients (81 eyes) with far-advanced open-angle glaucoma were followed up. The patients were divided into two groups by the treatment they received. In group 1 (41 patients, 41 eyes) a complex treatment scheme was applied, which included surgical, medicinal, and physiotherapeutic measures, in particular, sinus trabeculectomy (STE) plus posterior scleral trepanation (PST), a 10-day course of subconjunctival Cytoflavin 10 mg 0.5 ml, and magnetolaser stimulation of the optic nerve. Group 2 (controls) consisted of the rest 40 patients (40 eyes), who received just STE and PST.
Results:
The combination approach has yielded visual improvements and glaucoma stabilization in 87% of patients from group 1 by the end of the first year of follow-up, while in group 2 positive changes were found in only 68% of patients.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Electron Transport Chain: Complex I and II
ROS generation is regulated and maintained at moderate levels necessary...
Radical Autoxidation
Ophthalmic Drug Delivery Systems

