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Xanthogranulomatous pancreatitis mimicking a malignant solid tumour.
Viswanath Atreyapurapu1, Abhinav Keshwani2, Ramachandra Lingadakai1
1Department of General Surgery, Kasturba Medical College, Manipal, Karnataka, India.
BMJ Case Reports
|April 1, 2016
Summary
Xanthogranulomatous pancreatitis (XGP) is a rare pancreatic condition. This case highlights XGP
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Xanthogranulomatous inflammation typically affects abdominal viscera but rarely the pancreas.
- Pancreatic masses often raise suspicion for malignancy, necessitating accurate diagnosis.
Observation:
- A 60-year-old male presented with epigastric pain and vomiting.
- Abdominal CT revealed an ill-defined pancreatic uncinate process mass, mimicking malignancy.
Findings:
- The patient underwent Whipple's pancreaticoduodenectomy.
- Final pathological diagnosis confirmed xanthogranulomatous pancreatitis (XGP), not pancreatic cancer.
Implications:
- XGP should be considered in the differential diagnosis of pancreatic masses lacking typical malignant features.
- Duodenum-preserving pancreatic surgery may be a viable option for XGP.
- This case expands the understanding of rare pancreatic inflammatory conditions.

