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Updated: Mar 23, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Transgender men and pregnancy
Juno Obedin-Maliver1, Harvey J Makadon2
1Department of Medicine, University of California San Francisco, San Francisco, CA, USA; Department of Gynecology, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
This commentary offers guidance for clinicians on transgender men's reproductive health. It covers preconception, pregnancy, and postpartum care, emphasizing gender-affirming practices for a positive perinatal experience.
Area of Science:
- Medical Science
- Reproductive Health
- Gender Studies
Background:
- Transgender individuals face ongoing stigma and healthcare access challenges.
- There is increasing interest in improving transgender health in the US.
- This commentary focuses on guiding clinicians in caring for transgender men during pregnancy.
Conclusions:
- Comprehensive, gender-affirming care is essential for transgender men throughout the perinatal period.
- Clinicians need specific guidance to support transgender men's reproductive health needs.
- Further research is needed on delivery modes and their impact on gender dysphoria.
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