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Updated: Mar 23, 2026

Designing Silk-silk Protein Alloy Materials for Biomedical Applications
Published on: August 13, 2014
Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups-from structural to
1School of Chemistry, University of Birmingham, Edgbaston B15 2TT, UK.
Abstract:
Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.
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