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Updated: Mar 23, 2026

2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications
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2D-HELS MS Seq: A General LC-MS-Based Method for Direct and de novo Sequencing of RNA Mixtures with Different Nucleotide Modifications

Published on: July 10, 2020

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Sequence mapping of transfer RNA chemical modifications by liquid chromatography tandem mass spectrometry

Robert Ross1, Xiaoyu Cao1, Ningxi Yu1

  • 1Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, PO Box 210172, University of Cincinnati, Cincinnati, OH 45221-0172, United States.

Methods (San Diego, Calif.)
|April 2, 2016
PubMed

Keywords:
LC–MS/MSModified basesModified nucleosidesRNA sequencingTandem mass spectrometrytRNA

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