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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

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Associations between increased renal resistive index and cardiovascular events

Kaoru Komuro1, Noriko Yokoyama2, Misaki Shibuya2

  • 1Department of Cardiology, National Hospital Organization Hakodate Hospital, 18-16 Kawahara, Hakodate, Hokkaido, 041-8512, Japan. kkaoru@hnh.hosp.go.jp.

Journal of Medical Ultrasonics (2001)
|April 2, 2016
PubMed

Insights

Renal resistive index (RI) is a valuable marker for predicting cardiovascular events in patients with cardiovascular disease (CVD). Higher RI indicates impaired kidney function and increased cardiac risk.

Area of Science:

  • Nephrology
  • Cardiology
  • Medical Imaging

Background:

  • Chronic kidney disease (CKD) is a significant risk factor for cardiovascular disease (CVD).
  • Renal resistive index (RI), measured by Doppler ultrasonography, is linked to renal impairment.
  • The relationship between RI, cardiac function, and cardiac events in CVD patients requires further investigation.

Purpose of the Study:

  • To investigate the association between renal resistive index (RI) and cardiac function in patients with CVD.
  • To evaluate the predictive utility of RI for cardiac events in this population.

Main Methods:

  • 452 patients with CVD underwent renal Doppler ultrasonography and echocardiography.
  • Correlations between RI, serum creatinine, and estimated glomerular filtration rate (eGFR) were analyzed.
  • RI was compared between patients who experienced cardiovascular events and matched controls.

Main Results:

  • RI showed significant but moderate correlations with serum creatinine and eGFR.
  • RI was positively correlated with age, left atrial volume index, left ventricular mass index, and the E/e' ratio.
  • RI was significantly higher in patients hospitalized with cardiovascular events compared to controls, despite similar age and eGFR.

Conclusions:

  • Renal RI reflects intrarenal hemodynamic impairment not fully captured by eGFR alone.
  • Assessing renal RI can augment prognostic estimates for patients with CVD.
Abstract

Keywords:
Cardiac eventsCardiovascular diseaseRenal Doppler ultrasonographyResistive index

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