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Bone Disorders

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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Related Experiment Video

Updated: Mar 23, 2026

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

Published on: May 16, 2016

Canine osteoarthritis

Hannah Doit¹, Rachel Dean¹

¹Centre for Evidence-based Veterinary Medicine, University of Nottingham, School of Veterinary Medicine and Science, Sutton Bonington Campus, Leicestershire LE12 5RD

The Veterinary Record

|April 2, 2016

Summary

No abstract available in PubMed .

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