Related Experiment Video
Updated: Mar 23, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Paroxysmal Amnesia Attacks due to Hashimoto's Encephalopathy
Pelin Nar Senol1, Aylin Bican Demir1, Ibrahim Bora1
1Department of Neurology, Faculty of Medicine, Uludag University, 16285 Bursa, Turkey.
Abstract:
Hashimoto's encephalopathy is a rare disease which is thought to be autoimmune and steroid responsive. The syndrome is characterized by cognitive impairment, encephalopathy, psychiatric symptoms, and seizures associated with increased level of anti-thyroid antibodies. The exact pathophysiology underlying cerebral involvement is still lesser known. Although symptoms suggest a nonlesional encephalopathy in most of the cases, sometimes the clinical appearance can be subtle and may not respond to immunosuppressants or immunomodulatory agents. Here we report a case who presented with drowsiness and amnestic complaints associated with paroxysmal electroencephalography (EEG) abnormalities which could be treated only with an antiepileptic drug.
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