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High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Published on: March 24, 2015

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Interferon lambda and hepatitis C virus core protein polymorphisms associated with liver cancer.

João Paulo Moreira1, Fernanda de Mello Malta1, Márcio Augusto Diniz2

  • 1Laboratory of Tropical Gastroenterology and Hepatology "João Alves de Queiroz and Castorina Bittencourt Alves", LIM-07, Institute of Tropical Medicine, University of São Paulo, São Paulo, Brazil; Department of Gastroenterology, University of São Paulo, School of Medicine, São Paulo, Brazil.

Virology
|April 2, 2016
PubMed
Summary

Hepatitis C virus (HCV) infection can lead to liver cancer. Specific Interferon lambda (IFNL) gene variations and HCV core protein mutations may increase the risk of developing hepatocellular carcinoma (HCC).

Keywords:
Chronic hepatitisHepatitis C virusImmune responsesInfectionMutationOncogenesis

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