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Updated: Mar 23, 2026

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Lessons Learned from Traditional NOTES: A Historical Perspective.

Robert H Hawes1

  • 1Center for Interventional Endoscopy, Florida Hospital Orlando, 601 E. Rollins St, Orlando, Florida 32803, USA.

Gastrointestinal Endoscopy Clinics of North America
|April 3, 2016
PubMed
Summary
This summary is machine-generated.

Natural orifice surgery, pioneered by Kantsevoy and Kalloo, involves endoscopic procedures through body orifices. The original concept focused on flexible endoscopic surgery via the mouth into the peritoneal cavity.

Keywords:
Natural orifice surgeryNatural orifice transluminal endoscopic surgery (NOTES)Therapeutic endoscopyWhite paper

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Area of Science:

  • Minimally Invasive Surgery
  • Gastroenterology
  • Surgical Innovation

Background:

  • The concept of natural orifice surgery emerged in the late 1990s.
  • The Apollo Group was formed in 1997 by surgeons dedicated to advancing therapeutic endoscopy.
  • Innovation in techniques and technologies was central to their mission.

Observation:

  • The initial meeting to discuss natural orifice surgery was held in 1998.
  • The original concept involved per-oral passage of a flexible endoscope.
  • The goal was to access the peritoneal cavity via a gastrostomy.

Findings:

  • Flexible endoscopic surgery was proposed as a key technique.
  • Access to the peritoneal cavity was envisioned through the stomach.
  • The gastrostomy route was identified for entry.

Implications:

  • This laid the groundwork for natural orifice transluminal endoscopic surgery (NOTES).
  • It represented a significant shift towards less invasive surgical approaches.
  • The development paved the way for future endoscopic innovations.