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Boost for Alginate Encapsulation in Beta Cell Transplantation
Daniel Pipeleers1, Bart Keymeulen1
1Diabetes Research Center, Brussels Free University and University Hospital Brussels, Center for Beta Cell Therapy in Diabetes, 1090 Brussels, Belgium.
Trends in Endocrinology and Metabolism: TEM
|April 3, 2016
Abstract:
A recent study reported that encapsulation of human embryonic stem cell (hESC)-derived beta cells by a novel alginate formula protects against foreign body reactivity in immune-competent mice. Intraperitoneal implants corrected a diabetic state for at least 6 months. These observations will stimulate the development of alginate encapsulation towards novel cell therapy protocols for treating type 1 diabetes (T1DM).
