Related Experiment Video

Updated: Mar 23, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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Chemical synthesis of RNA with site-specific methylphosphonate modifications

Sara Flür1, Ronald Micura1

  • 1Institute of Organic Chemistry and Center for Molecular Biosciences, CMBI, Leopold-Franzens University, Innrain 80-82, 6020 Innsbruck, Austria.

Methods (San Diego, Calif.)
|April 3, 2016
PubMed

Keywords:
MethylphosphonateRNA solid-phase synthesisStereochemical assignmentThermodynamic base pairing stability

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