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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Related Experiment Video

Updated: Mar 23, 2026

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
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Clinical repigmentation patterns in paediatric vitiligo.

E Y Gan1, T Gahat2, M Cario-André3

  • 1Department of Paediatric Dermatology, National Centre for Rare Skin Disorders, Hôpital Pellegrin-Enfants, CHU de Bordeaux, Bordeaux, France. emily.ganyp@gmail.com.

The British Journal of Dermatology
|April 3, 2016
PubMed
Summary
This summary is machine-generated.

The most common vitiligo repigmentation pattern observed was combined. A new pattern, medium spotted repigmentation, was identified in areas with fewer hair follicles.

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Area of Science:

  • Dermatology
  • Clinical Research

Background:

  • Repigmentation is a key outcome in vitiligo treatment.
  • Limited clinical data exists on vitiligo repigmentation patterns.

Purpose of the Study:

  • To define vitiligo repigmentation patterns.
  • To correlate patterns with patient characteristics.

Main Methods:

  • Retrospective review of 109 vitiligo patients (2006-2014).
  • Analysis of clinical photographs and medical records.
  • Evaluation of 172 vitiligo lesions.

Main Results:

  • Combined repigmentation pattern was most frequent (62%).
  • Combined pattern more common in segmental vitiligo; diffuse pattern more frequent in nonsegmental.
  • A novel 'medium spotted repigmentation' pattern was observed.

Conclusions:

  • The combined repigmentation pattern is most prevalent.
  • Medium spotted repigmentation is a newly identified pattern requiring further investigation.