Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

9.9K
Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
9.9K
Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

2.1K
2.1K
Phosphodiester Linkages01:01

Phosphodiester Linkages

113.7K
Overview
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...
113.7K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.3K
4.3K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

5.9K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
5.9K
Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)01:22

Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)

1.7K
Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive.
The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the involved orbitals. The...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of Pyrrole-Sharing Fused Porphyrinoid Hybrids by Post-fabrication of Ni(II) Porphyrins.

Angewandte Chemie (International ed. in English)·2023
Same author

Di(p-dibenzi)[40]decaphyrin(1.0.0.0.0.1.0.0.0.0) Pd<sup>II</sup> Complex: A Weakly Hückel 38π-Aromatic Macrocycle.

Chemistry, an Asian journal·2023
Same author

Cyclic Azobenzene-BODIPY Hybrids.

Chemistry (Weinheim an der Bergstrasse, Germany)·2023
Same author

Stable Antiaromatic [24]Hexaphyrin(1.1.0.0.1.0) and Its Metal Complexes.

Organic letters·2023
Same author

Synthesis of Naphthalene- and Phenanthrene-Fused Smaragdyrins and Their BF<sub>2</sub> Complexes.

Chemistry, an Asian journal·2023
Same author

Publisher Correction: Doubly N-confused and ring-contracted [24] hexaphyrin Pd-complexes as stable antiaromatic N-confused expanded porphyrins.

Nature communications·2023

Related Experiment Video

Updated: Mar 23, 2026

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
11:22

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Published on: January 30, 2018

10.7K

Triply Linked Corrole Dimers.

Shota Ooi1, Takayuki Tanaka2, Kyu Hyung Park3

  • 1Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan.

Angewandte Chemie (International Ed. in English)
|April 3, 2016
PubMed
Summary

Researchers synthesized novel triply linked 2H-corrole dimers via oxidation, revealing nonaromatic electronic networks. Subsequent reduction yielded unstable aromatic 3H-corrole dimers, with zinc complexes offering rare nonaromatic examples.

Keywords:
aromaticityconjugationcorrolesoxidationporphyrinoids

More Related Videos

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.6K
Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.7K

Related Experiment Videos

Last Updated: Mar 23, 2026

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions
11:22

Using Three-color Single-molecule FRET to Study the Correlation of Protein Interactions

Published on: January 30, 2018

10.7K
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.6K
Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.7K

Area of Science:

  • Organic Chemistry
  • Supramolecular Chemistry
  • Coordination Chemistry

Background:

  • Corrole dimers are complex macrocyclic compounds with diverse electronic properties.
  • Understanding the synthesis and stability of linked corrole systems is crucial for developing new functional materials.

Purpose of the Study:

  • To synthesize and characterize novel triply linked 2H-corrole dimers.
  • To investigate the electronic properties and stability of these nonaromatic corrole systems.
  • To explore the formation of metal complexes with these unique corrole structures.

Main Methods:

  • Oxidation of singly linked corrole dimers using DDQ (2,3-dichloro-5,6-dicyano-1,4-benzoquinone).
  • Reduction of 2H-corrole dimers using sodium borohydride (NaBH4).
  • Spectroscopic characterization including 1H NMR and absorption spectroscopy.
  • Synthesis and characterization of bis(zinc(II)) complexes.

Main Results:

  • Successful synthesis of meso-meso, β-β, β-β triply linked 2H-corrole dimers with nonaromatic electronic networks.
  • 2H-corrole dimers showed characteristic NMR and absorption spectra.
  • Reduction to aromatic 3H-corrole dimers resulted in unstable compounds easily re-oxidized.
  • Rare examples of nonaromatic bis(zinc(II)) corrole complexes were synthesized and characterized.

Conclusions:

  • The study presents a novel route to triply linked corrole dimers with distinct nonaromatic electronic properties.
  • The interconversion between nonaromatic 2H-corrole and unstable aromatic 3H-corrole dimers highlights unique reactivity.
  • The synthesized nonaromatic zinc(II) corrole complexes represent valuable additions to the field of metalloporphyrinoids.