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Rationale and design of the ARCUS: Effects of trAnsRadial perCUtaneouS coronary intervention on upper extremity

Eva M Zwaan1, Alexander J J IJsselmuiden1, Joost van Rosmalen2

  • 1Department of Cardiology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|April 3, 2016
PubMed

Insights

Transradial Percutaneous Coronary Intervention (TR-PCI) may impact upper extremity function. This study investigates potential access-site morbidity and functional outcomes after TR-PCI, aiming to optimize the procedure.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Rehabilitation Medicine

Background:

  • Transradial Approach (TRA) is increasingly preferred for percutaneous coronary intervention.
  • While TRA offers potential benefits, its precise impact on upper extremity function remains unclear.

Purpose of the Study:

  • To comprehensively assess access-site morbidity following Transradial Percutaneous Coronary Intervention (TR-PCI).
  • To evaluate the effects of TR-PCI on overall upper extremity function.
  • To identify factors influencing functional outcomes post-TR-PCI.

Main Methods:

  • A multicenter prospective cohort study (ARCUS trial) involving patients undergoing TR-PCI.
  • Clinical outcomes monitored for 6 months, with a primary endpoint at 2 weeks.
  • Assessment of anatomical integrity, strength, range of motion, coordination, sensibility, pain, and daily functioning using physical exams and validated questionnaires.

Main Results:

  • The study will provide detailed insights into upper extremity function post-TR-PCI.
  • Data will elucidate the relationship between TR-PCI and functional deficits or morbidity.
  • Procedural and material details will be recorded to analyze their influence on outcomes.

Conclusions:

  • Findings will clarify the impact of TR-PCI on upper extremity function.
  • Results can guide optimization of TR-PCI techniques.
  • The study aims to improve functional outcomes and prevent upper extremity morbidity.
Abstract

Keywords:
percutaneous coronary interventiontransradialupper extremity dysfunction

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