Transient Deformation of Neutrophils in Kawasaki Disease
Yumi Koike1, Ryu Yanagisawa2, Yoshifumi Ogiso3
1Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
Abstract:
In the treatment of Kawasaki disease, resistance to high-dose immunoglobulin intravenous (IGIV) can occur. The neutrophil morphology analyses in 17 patients revealed that transient pseudo-Pelger-Huët anomaly was more frequently detected in the IGIV-resistant group. This finding may aid the prediction of IGIV resistance.
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