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Updated: Mar 23, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Sella size and jaw bases - Is there a correlation???
Neha1, Subraya Mogra2, Vorvady Surendra Shetty2
1Department of Orthodontics and Dentofacial Orthopedics, Maulana Azad Institute of Dental Sciences, New Delhi, India.
The study found that while sella turcica dimensions varied slightly across malocclusion types, mandible size showed a significant correlation with sella dimensions, suggesting a link between jaw structure and this key cephalometric landmark.
Area of Science:
- Cephalometric analysis
- Orthodontics
- Craniometry
Background:
- Sella turcica is a critical cephalometric landmark.
- Previous research explored sella dimensions in relation to malocclusion.
- No studies have directly compared sella size with jaw bases determining malocclusion types.
Purpose of the Study:
- To investigate the correlation between sella turcica dimensions and jaw base sizes.
- To determine if sella size differs significantly across different malocclusion classes (I, II, III).
- To identify potential relationships between specific jaw structures and sella morphology.
Main Methods:
- Lateral cephalograms of 110 adult patients (40 Class I, 40 Class II, 30 Class III) were analyzed.
- Measurements included sella length, width, height, and area, along with maxillary length, mandibular ramus height, and body length.
- Statistical analysis involved one-way ANOVA for comparing sella dimensions across malocclusion types and Pearson correlation for assessing relationships between jaw and sella sizes.
Main Results:
- Mean sella length, width, and area were largest in Class III, followed by Class I, and smallest in Class II, though not statistically significant.
- Three out of four sella dimensions significantly correlated with mandibular ramus and body length.
- Only one sella dimension showed a significant correlation with maxillary length.
Conclusions:
- The mandible demonstrates a definite and stronger correlation with sella turcica size compared to the maxilla.
- Consistent ratios were observed between mandibular ramus/body length and sella area across all malocclusion types.
- These findings suggest a potential link between mandibular development and sella turcica morphology.
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