Gullo's Syndrome: A Case Report.

Area of Science:

• Gastroenterology
• Internal Medicine
• Biochemistry

Background:

• Benign Pancreatic Hyperenzymemia (BPH), also known as Gullo's Syndrome, is a recently identified clinical entity.
• It is defined by persistently elevated serum pancreatic enzymes (amylase and lipase) in the absence of any evidence of pancreatic pathology or disease.

Observation:

• A 42-year-old female patient presented with symptoms of pneumonia.
• Routine investigations revealed persistently elevated serum amylase and lipase levels.
• Extensive workup for secondary causes of hyperenzymemia yielded no evidence of pancreatic disease.

Findings:

• The patient was diagnosed with Gullo's Syndrome after a year of follow-up, during which pancreatic enzyme levels remained elevated.
• This case represents the first reported instance of Gullo's Syndrome in the Indian subcontinent.

Implications:

• Gullo's Syndrome is a diagnosis of exclusion, necessitating awareness of differential diagnoses for elevated pancreatic enzymes.
• Clinicians must consider BPH in patients with unexplained hyperenzymemia, particularly when other causes are ruled out.
• This case expands the geographical reporting of BPH and underscores its recognition in diverse clinical settings.