Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.3K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.3K
Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

14.6K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
14.6K
Skeletal Muscle Relaxants: Adverse Effects01:21

Skeletal Muscle Relaxants: Adverse Effects

1.0K
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
1.0K
Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

1.1K
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
1.1K
The Functions of the Skeletal System01:22

The Functions of the Skeletal System

6.7K
The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
6.7K
Classification of Skeletal Muscle Relaxants01:28

Classification of Skeletal Muscle Relaxants

3.3K
Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[A comparative assessment of microbiocenosis of saliva and oropharynx in patients with migraine].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2024
Same author

[Features of fibromyalgia in patients with rheumatoid arthritis].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2024
Same author

[Botulinum toxin type A (Relatox) in transition from medication overuse to non-overuse status in patients with chronic migraine: a subgroup analysis of phase IIIb randomized single-blind multicenter active-controlled parallel-group trial].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2023
Same author

[The role of food allergy as a provoking factor of migraine].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2023
Same author

[Botulinum toxin type A (Relatox) in the treatment of chronic migraine in adults: results of phase IIIb, randomized, one-blind, multicenter, active-controlled, parallel-group trial].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2023
Same author

[The state of the oropharyngeal microbiome in patients with migraine].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2023

Related Experiment Video

Updated: Mar 23, 2026

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

6.3K

[Muscle-skeletal pain].

M V Vygonskaya1, E G Filatova1

  • 1VGOU VPO 'Pervyj Moskovskij gosudarstvennyj meditsinskij universitet im. I.M. Sechenova', Moskva.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|April 5, 2016
PubMed
Summary

This study differentiates specific and nonspecific low back pain using red flags and addresses pain chronification with yellow flags. It highlights the biopsychosocial model and ketorolac

Area of Science:

  • Investigates complex aspects of low back pain, encompassing specific and nonspecific etiologies.
  • Explores pathogenetic mechanisms of chronic muscle/skeletal pain.

Context:

  • Differentiates specific and nonspecific low back pain utilizing the 'red flags' system.
  • Examines causes of pain chronification through the 'yellow flags' system.
  • Emphasizes the necessity of a biopsychosocial model in pain management.

Purpose:

  • To analyze the complex factors contributing to low back pain.
  • To discuss the role of multiple mechanisms in chronic pain pathogenesis.
  • To evaluate the efficacy and safety of ketorolac for nonspecific muscle/skeletal pain.

Summary:

  • Highlights the 'red flags' system for distinguishing low back pain types.
  • Considers 'yellow flags' for understanding pain chronification and the biopsychosocial model.

More Related Videos

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
08:03

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

9.0K
Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation
06:28

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

1.6K

Related Experiment Videos

Last Updated: Mar 23, 2026

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

6.3K
Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
08:03

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Published on: February 22, 2019

9.0K
Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation
06:28

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

1.6K
  • Demonstrates high efficacy and safety of ketorolac in treating nonspecific muscle/skeletal pain.

    • Impact:

    • Provides insights into differentiating low back pain types for targeted treatment.
    • Underscores the importance of a comprehensive biopsychosocial approach to chronic pain.
    • Supports the use of ketorolac as an effective and safe option for muscle/skeletal pain.