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Updated: Jul 29, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
Published on: August 31, 2014
Replication is about effect size: Comment on Maxwell, Lau, and Howard (2015)
1Fordham University.
Abstract:
The view that a single study can be trusted is an attractive but false promise provided by null hypothesis testing. The replication question should be to what extent investigators can reproduce effect sizes and how narrow their 95% confidence interval can become. Cumulative meta-analyses will enable us to determine how replicable psychological effects are and what their effect size is.
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