Related Experiment Video
Updated: Mar 23, 2026
08:07
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
7.8K
Multifocal low-grade central osteosarcoma: a rare case.
Richard Boyle1, Bruno Giuffre2, S Fiona Bonar3
1Department of Orthopaedics, The Chris O'Brien Lifehouse and Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW, 2050, Australia. Rich_boyle@hotmail.com.
Skeletal Radiology
|April 6, 2016
Summary
Low-grade central osteosarcoma (LGCOS), a rare bone cancer, can present multifocally. Close monitoring of incidental findings is crucial for early detection and management of this uncommon condition.
Area of Science:
- Orthopedic Oncology
- Skeletal Radiology
Background:
- Low-grade central osteosarcoma (LGCOS) is an uncommon malignant bone tumor.
- Multifocal presentation of LGCOS is exceptionally rare.
Observation:
- A case of multifocal LGCOS in two distinct skeletal locations is presented.
- Lesions were incidental findings during imaging for unrelated trauma.
- Initial imaging revealed small, seemingly innocuous, and clinically quiescent lesions.
Findings:
- The multifocal nature of LGCOS was confirmed.
- The lesions demonstrated slow growth or stability over time.
- Multimodal surveillance imaging was essential for tracking lesion evolution.
Implications:
- Highlights the importance of recognizing LGCOS, even when presenting as incidental findings.
- Emphasizes the diagnostic value of vigilant, interval-based imaging surveillance.
- Suggests that multifocal LGCOS may have an indolent clinical course requiring careful monitoring.
