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Coccidiodal meningitis and pregnancy: a case report
C M Peterson1, S L Johnson, J V Kelly
1Department of Obstetrics and Gynecology, Maricopa Medical Center, Phoenix, Arizona.
Obstetrics and Gynecology
|May 1, 1989
Summary
Coccidioidal meningitis in pregnancy is rare but treatable. Intrathecal amphotericin B successfully treated a pregnant woman with this fungal infection during two pregnancies.
Area of Science:
- Mycology
- Infectious Diseases
- Obstetrics and Gynecology
Background:
- Coccidioidal meningitis is a serious fungal infection of the central nervous system.
- Pregnancy presents unique challenges for managing infectious diseases due to potential risks to the fetus.
Purpose of the Study:
- To report a successful treatment of coccidiodal meningitis during two successive pregnancies.
- To highlight the safety and efficacy of intrathecal amphotericin B in pregnant patients.
Main Methods:
- Case report of a woman diagnosed with coccidiodal meningitis.
- Treatment administered included intrathecal amphotericin B.
- Pregnancy outcomes were monitored throughout both pregnancies.
Main Results:
- The patient underwent successful treatment for coccidiodal meningitis.
- The treatment did not adversely affect either pregnancy.
- Two successful pregnancies were completed under treatment.
Conclusions:
- Intrathecal amphotericin B can be a safe and effective treatment option for coccidiodal meningitis in pregnant women.
- Successful management of coccidiodal meningitis during pregnancy is achievable.
- This case supports the use of targeted antifungal therapy in obstetric infectious disease management.