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Eosinophilic fasciitis during pregnancy.

H S Amdur1, R E Levin

  • 1Thames Gynecologic Group, New London, Connecticut.

Obstetrics and Gynecology
|May 1, 1989
PubMed
Summary

This case report details the first instance of eosinophilic fasciitis during pregnancy, outlining its obstetric management. The rare condition involves painful extremity swelling and skin hardening, treatable with prednisone.

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Area of Science:

  • Rheumatology
  • Obstetrics
  • Dermatology

Background:

  • Eosinophilic fasciitis is a rare connective tissue disorder.
  • It presents with painful extremity swelling, skin induration, and peripheral eosinophilia.
  • Diagnosis requires deep fascia biopsy showing inflammatory infiltrates.

Observation:

  • This report describes the first case of eosinophilic fasciitis occurring during pregnancy.
  • The obstetric management strategies for this unique clinical scenario are presented.

Findings:

  • Eosinophilic fasciitis is characterized by pain, swelling, and skin hardening.
  • Key laboratory findings include eosinophilia, hypergammaglobulinemia, and elevated ESR.
  • Histopathology reveals plasma cells, lymphocytes, and eosinophils in the deep fascia.

Implications:

  • This case highlights the importance of recognizing eosinophilic fasciitis in pregnant patients.
  • Effective obstetric management is crucial for favorable maternal and fetal outcomes.
  • Prednisone remains the primary treatment, with awareness of potential associated complications like carpal tunnel syndrome.

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