Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

BioMedGraphica: an all-in-one platform for joint textual biomedical prior knowledge and numeric graph generation.

Bioinformatics (Oxford, England)·2026
Same author

Functional significance of the aryl hydrocarbon receptor in oncogenic signaling pathways.

Carcinogenesis·2026
Same author

OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Graph Language Foundation Modeling.

Research square·2026
Same author

Silencing CD24 Inhibits Proliferation, Migration, and Chemoresistance in Triple-Negative Breast Cancer Cells.

Pharmaceutical research·2026
Same author

Modulating <i>Bacteroides</i> to boost anti-PD-1 immunotherapy in HCC.

Journal for immunotherapy of cancer·2026
Same author

Characterization of a bronchoscopically induced transgenic lung cancer pig model for human translatability.

Lab animal·2025

Related Experiment Video

Updated: Mar 23, 2026

Adaptation of Semiautomated Circulating Tumor Cell CTC Assays for Clinical and Preclinical Research Applications
14:14

Adaptation of Semiautomated Circulating Tumor Cell CTC Assays for Clinical and Preclinical Research Applications

Published on: February 28, 2014

16.3K

Perioperative circulating tumor cell detection: Current perspectives.

Jussuf T Kaifi1,2, Guangfu Li1,3, Gary Clawson4

  • 1a Hugh E. Stephenson Jr., M.D. , Department of Surgery , University of Missouri , Columbia , MO , USA.

Cancer Biology & Therapy
|April 6, 2016
PubMed
Summary
This summary is machine-generated.

Detecting circulating tumor cells (CTCs) during surgery offers a unique chance to improve cancer prognostication. Analyzing these cells can guide future molecular therapies and reveal immune evasion strategies.

Keywords:
Circulating tumor cellsdisseminated tumor cellsmetastasectomysurgery

More Related Videos

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
06:53

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

9.3K
Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
07:32

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples

Published on: June 15, 2012

27.3K

Related Experiment Videos

Last Updated: Mar 23, 2026

Adaptation of Semiautomated Circulating Tumor Cell CTC Assays for Clinical and Preclinical Research Applications
14:14

Adaptation of Semiautomated Circulating Tumor Cell CTC Assays for Clinical and Preclinical Research Applications

Published on: February 28, 2014

16.3K
Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
06:53

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

9.3K
Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
07:32

Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples

Published on: June 15, 2012

27.3K

Area of Science:

  • Oncology
  • Surgical Oncology
  • Cancer Diagnostics

Background:

  • Primary cancer resections and metastasectomies improve survival but recurrences are common.
  • Circulating tumor cells (CTCs) are independent prognostic markers in various cancers.
  • Perioperative sampling offers a unique window for enhanced tumor cell capture.

Purpose of the Study:

  • To review the diagnostic and therapeutic potential of perioperative tumor isolation.
  • To highlight future research directions for disseminated cancer cells.
  • To identify targets for molecular therapy and understand immune escape.

Main Methods:

  • Review of existing literature on perioperative tumor cell isolation.
  • Analysis of the role of circulating tumor cells in cancer prognostication.
  • Discussion of single disseminated cancer cell characterization techniques.

Main Results:

  • Perioperative sampling can increase the efficiency of capturing circulating tumor cells.
  • Circulating tumor cells hold significant diagnostic and therapeutic potential.
  • Characterization of single cells is crucial for personalized treatment strategies.

Conclusions:

  • Perioperative isolation of circulating tumor cells presents a promising avenue for improved cancer management.
  • Future studies should focus on single disseminated cancer cell analysis for targeted therapies.
  • Understanding immune escape mechanisms is key to overcoming treatment resistance.