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Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

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Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

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AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
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Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Related Experiment Video

Updated: Mar 23, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Comorbidity in rheumatoid arthritis.

Carl Turesson1

  • 1Rheumatology, Department of Clinical Sciences, Malmö, Faculty of Medicine, Lund University, Sweden; and Department of Rheumatology, Skåne University Hospital, Malmö, Sweden.

Swiss Medical Weekly
|April 6, 2016
PubMed
Summary

Rheumatoid arthritis (RA) management has improved, but comorbidity remains a significant challenge. Early detection and multidisciplinary collaboration are crucial for better patient outcomes in managing RA and its related conditions.

Area of Science:

  • Rheumatology
  • Immunology
  • Public Health

Background:

  • Rheumatoid arthritis (RA) is a chronic inflammatory disease linked to increased comorbidity risks.
  • Disease severity in RA predicts cardiovascular disease, infections, and lymphoma.
  • Despite improved pharmacotherapy, comorbidity persists as a major issue for RA patients.

Purpose of the Study:

  • To highlight the ongoing challenge of comorbidity in rheumatoid arthritis.
  • To emphasize the importance of register-based studies for evaluating treatment efficacy and safety in patients with coexisting diseases.
  • To advocate for multidisciplinary collaboration in RA management.

Main Methods:

  • Utilizing register-based observational studies.
  • Analyzing data on comorbidity prevalence and impact in RA patients.

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  • Reviewing trends in clinical outcomes and pharmacotherapy effectiveness.

    • Main Results:

    • Clinical outcomes for RA patients have improved due to advanced pharmacotherapy.
    • Comorbidity remains a significant clinical issue impacting many RA patients.
    • Chronic inflammation plays a key role in RA pathology and associated comorbidities.

    Conclusions:

    • Multidisciplinary collaboration is essential for the prevention and early detection of comorbidities in RA.
    • Register-based studies provide valuable insights into managing RA patients with coexisting conditions.
    • Further strategies are needed to comprehensively manage RA and its associated health risks.