Related Experiment Video
Updated: Mar 23, 2026

Author Spotlight: Efficiently Eliminating Bacteriophages from Infected Salmonella Cultures Using Lipopolysaccharides
Published on: June 28, 2024
An Overview on Bacteriophages: A Natural Nanostructured Antibacterial Agent
Vaibhav Rastogi1, Pragya1, Navneet Verma1
1Department of Pharmacy, IFTM University, Moradabad, Uttar Pradesh, 244001. India.
Background:
Recent advances in the field of bionanomedicine not only enable us to produce biomaterials but also to manipulate them at molecular level. Viruses particularly bacteriophages are a promising nanomaterial that can be functionalized with great precision. Bacteriophages are the natural antimicrobial agents that fight against antibiotic resistant bacteria which cause infections in animals, humans, or in crops of agricultural value. The idea of utilizing bacteriophages as therapeutic agents is due to their ability to kill bacteria at the end of the infectious cycle.
Objective:
This paper reviewed the general biology of bacteriophages and the presence of receptors on the bacteria which are necessary for the recognition and adsorption of bacteriophages. Pharmacokinetics and therapeutic potential of bacteriophages administered through various routes in treating diverse bacterial infections is also reviewed along with the problems associated with bacteriophage therapy.
Conclusion:
Among various routes of administration, parenteral route is found to be the most thriving route for the treatment of systemic infections whereas oral route is meant to treat gastrointestinal infections and; local delivery (skin, nasal, ears) of phages has proven its potency to treat topical infections.
Related Concept Videos
Lytic Cycle of Bacteriophages
DNA Bacteriophages
Biological Methods for Microbial Control
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Lysogenic Cycle of Bacteriophages
Microbial Corrosion

