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Predictors of blood pressure at 7-13 years: The "new millennium baby" study
P Brambilla1, G Bedogni2, A Pietrobelli3
1Azienda Sanitaria Locale 2, Melegnano, Milan, Italy.
Insights
Introducing complementary feeding (CF) between 5-6 months is linked to lower blood pressure (BP) in children. This association appears independent of body mass index (BMI), suggesting early nutrition impacts long-term cardiovascular health.
Area of Science:
- Pediatrics
- Public Health
- Nutritional Science
Background:
- Childhood blood pressure (BP) is influenced by various factors.
- Understanding early life determinants of BP is crucial for preventing noncommunicable diseases.
- Body Mass Index (BMI), early feeding practices, lifestyle, and parental factors are potential influences.
Purpose of the Study:
- To investigate the association between blood pressure (BP) in children aged 7-13 years.
- To examine the roles of body mass index (BMI), early feeding, lifestyle, and parental characteristics in BP.
- To explore potential mediation effects of BMI on the relationship between early feeding and BP.
Main Methods:
- A retrospective and cross-sectional cohort study of 1294 children born between 2000-2004.
- Data collected included breast-feeding duration, complementary feeding (CF) introduction, screen time, sports activity, parental education, smoking, and obesity.
- Statistical analyses included multivariable linear regression and mediation analysis.
Main Results:
- Complementary feeding (CF) introduction at 5-6 months was a negative predictor of systolic and diastolic BP (p < 0.001).
- Higher Body Mass Index (BMI) was a positive predictor of BP (p < 0.001), while parental hypertension predicted diastolic BP (p < 0.05).
- Predictors of BMI included birth weight, screen time, and parental obesity/smoking (p < 0.001); breast-feeding had no effect on BP or BMI.
Conclusions:
- Introducing complementary feeding (CF) between 5-6 months may be associated with lower childhood BP.
- The effect of CF on BP appears independent of BMI.
- Low screen time is linked to lower BMI, and CF timing may influence noncommunicable disease risk.
Background And Aims:
The purpose of this study is to evaluate the association between blood pressure (BP) at 7-13 years of age and body mass index (BMI), early feeding, lifestyle indicators, and parental characteristics.
Methods And Results:
Retrospective plus cross-sectional cohort study was started in 1294 children born in 2000-2004, right from their birth in primary care settings. Early feeding was estimated by measuring breast-feeding (BF) duration, complementary feeding (CF) introduction time, and lifestyle indicators such as daily screen time and weekly extracurricular sports activity time. Parental education, smoking, and obesity-related diseases were also considered. Multivariable linear regression and mediation analysis were used. CF introduction at 5-6 months of age was a negative predictor of systolic and diastolic BP (mean systolic BP-standard deviation score (SDS) -0.38 [95% CI: -0.47, -0.29] (p < 0.001); mean diastolic BP-SDS -0.32 [95% CI: -0.40, -0.24]) (p < 0.001); BMI was a positive predictor of systolic and diastolic BP (p < 0.001); and parental hypertension was a positive predictor of diastolic BP (p < 0.05). Predictors of mean BMI-SDS at 7-13 years of age were birth weight, screen time, and parental obesity and smoking (p < 0.001). BF had no effect on BP or BMI. Mediation analysis showed virtually no indication of the effect of CF on BP mediated by BMI.
Conclusions:
CF introduction between 5 and 6 months of age could be associated with low BP at 7-13 years. The effect of CF on BP seems to be independent of BMI. Low screen time is associated with low BMI. CF time may play a role in the occurrence of surrogates of noncommunicable disorders in future.
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