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Related Experiment Video

Updated: Mar 23, 2026

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
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Parenteral trace element provision: recent clinical research and practical conclusions.

P Stehle1, B Stoffel-Wagner2, K S Kuhn1

  • 1Department of Nutrition and Food Sciences - Nutritional Physiology, University of Bonn, Bonn, Germany.

European Journal of Clinical Nutrition
|April 7, 2016
PubMed
Summary

Parenteral trace element provision is crucial for adult patients receiving nutrition therapy. Ensuring adequate daily intake of essential trace elements prevents deficiencies and malnutrition syndromes.

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Area of Science:

  • Clinical Nutrition
  • Trace Element Metabolism

Background:

  • Nine essential trace elements (selenium, zinc, copper, manganese, chromium, iron, molybdenum, iodine, fluoride) play vital roles in human metabolism.
  • Prolonged insufficient trace element supply during nutrition therapy can lead to deprivation, worsening existing conditions and causing malnutrition syndromes.

Purpose of the Study:

  • To systematically review recent clinical studies on parenteral trace element provision in adult patients.
  • To provide evidence-based conclusions for optimizing clinical practice regarding trace element supplementation.

Main Methods:

  • Systematic review of clinical studies.
  • Searches conducted on PubMed and Cochrane databases up to December 31, 2014.

Main Results:

  • Data from clinical studies on parenteral trace element provision were analyzed.
  • Identified the importance of trace elements in preventing malnutrition.

Conclusions:

  • All parenteral nutrition prescriptions should incorporate daily trace element doses.
  • Physiological doses of trace elements are recommended to prevent deprivation and imbalances.