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Development and validation of a correction equation for Corvis tonometry.

Akram Abdelazim Joda1,2, Mir Mohi Sefat Shervin3, Daniel Kook4

  • 1a School of Engineering , University of Liverpool , Liverpool , UK.

Computer Methods in Biomechanics and Biomedical Engineering
|April 7, 2016
PubMed
Summary

A new method corrects intraocular pressure (IOP) readings from the Corvis Tonometer, accounting for central corneal thickness (CCT) and age. This reduces measurement variability for more accurate IOP assessment.

Keywords:
Corvis STTonometrycorneaintraocular pressureocular biomechanics

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Corneal Biomechanics

Background:

  • Intraocular pressure (IOP) measurement is crucial for diagnosing and managing glaucoma.
  • Corvis Tonometer (CVS) provides IOP readings but can be influenced by central corneal thickness (CCT) and patient age.
  • Accurate IOP measurement is essential for effective glaucoma treatment.

Purpose of the Study:

  • To develop and validate a numerical method for correcting Corvis Tonometer (CVS) IOP measurements.
  • To account for the confounding effects of central corneal thickness (CCT) and age on IOP readings.
  • To improve the accuracy and reliability of IOP measurements in clinical practice.

Main Methods:

  • Finite element analysis (FEA) simulated corneal deformation under tonometric air pressure.
  • Simulations incorporated variations in IOP, CCT, corneal radius, and age.
  • An algorithm was derived to correct CVS-IOP based on CVS-IOP, CCT, and age.

Main Results:

  • Initial CVS-IOP measurements showed significant correlation with CCT and age.
  • The developed correction algorithm substantially reduced the correlation between corrected IOP and both CCT and age.
  • Validation on a clinical dataset of 634 eyes confirmed the algorithm's effectiveness.

Conclusions:

  • The developed algorithm successfully corrects Corvis Tonometer IOP measurements for CCT and age.
  • This correction method reduces the dependency of IOP readings on corneal properties and patient age.
  • The findings contribute to more accurate IOP assessment in a healthy European population.