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Related Concept Videos

Gallbladder01:17

Gallbladder

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The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
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Diseases of the Liver and Gallbladder01:26

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
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Gastritis-II: Pathophysiology01:17

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
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Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
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Clinicopathological Spectrum Of Gall Bladder Cancer In Kashmir - An Institutional Study.

R Makhdoomi1, N Bashir2, N Bhat3

  • 1Department of Pathology, Sher-i-Kashmir Institute of Medical Sciences, Kashmir.

The Gulf Journal of Oncology
|April 7, 2016
PubMed
Summary
This summary is machine-generated.

Gallbladder cancer, a common gastro-intestinal tumor, often presents late. This study analyzed 57 cases, finding adenocarcinomas were most common, with gallstones present in only 14% of cases.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Gallbladder cancer is an aggressive malignancy often diagnosed at advanced stages.
  • It ranks as the fifth most common gastro-intestinal tumor, causing significant mortality.
  • Early detection and understanding of clinicopathological features are crucial for improved outcomes.

Purpose of the Study:

  • To analyze the clinicopathological features of gallbladder cancer.
  • To determine the prevalence of different histological subtypes.
  • To investigate the association between gallstones and gallbladder cancer subtypes.

Main Methods:

  • Retrospective analysis of histopathological records from December 2009 to December 2013.
  • Inclusion of 57 diagnosed cases of gallbladder carcinoma.
  • Review of gross, histopathological, clinical, laboratory, radiological, and intra-operative findings.

Main Results:

  • Adenocarcinomas constituted 87.5% of all gallbladder carcinomas.
  • Gallstones were present in only 8 cases (14%) of the total cohort.
  • Other histological types included squamous cell carcinoma (4 cases) and small cell carcinoma (1 case).

Conclusions:

  • Adenocarcinoma is the predominant histological subtype of gallbladder cancer.
  • The association between gallstones and gallbladder cancer may be less prevalent than commonly believed.
  • Further research into the diverse etiology and presentation of gallbladder cancer is warranted.