Pediatric Patient With Altered Mental Status and Hypoxemia: Case Report

Jeremy M Root1, Marcela Vargas, Luigi R Garibaldi

  • 1From the *Department of Pediatrics, University of Pittsburgh School of Medicine; †Department of Pediatrics, Children's Hospital of Pittsburgh; ‡Division of Pediatric Endocrinology, Department of Pediatrics, University of Pittsburgh School of Medicine; and §Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Insights

Myxedema coma, a rare condition in children, can present with altered mental status. This case highlights the importance of considering severe hypothyroidism in pediatric patients with hypoxemia and influenza.

Area of Science:

  • Pediatric Endocrinology
  • Critical Care Medicine

Background:

  • Myxedema coma, a severe manifestation of hypothyroidism, is exceptionally rare in pediatric populations.
  • Prompt diagnosis and management are crucial for favorable outcomes in pediatric critical care.

Observation:

  • A 5-year-old girl presented with hypoxemia and altered mental status.
  • The patient was diagnosed with severe hypothyroidism and myxedema coma.
  • The condition occurred in the context of an acute influenza infection.

Findings:

  • This case underscores the rarity of myxedema coma in childhood.
  • Influenza infection can precipitate myxedema coma in susceptible pediatric patients.
  • Severe hypothyroidism requires urgent recognition and intervention.

Implications:

  • Myxedema coma should be included in the differential diagnosis for pediatric patients with altered mental status and organ dysfunction.
  • Early identification of severe hypothyroidism is vital in pediatric emergency settings.
  • This case emphasizes the need for heightened awareness of rare endocrine emergencies in children.

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