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Published on: May 16, 2015
Pediatric Patient With Altered Mental Status and Hypoxemia: Case Report
Jeremy M Root1, Marcela Vargas, Luigi R Garibaldi
1From the *Department of Pediatrics, University of Pittsburgh School of Medicine; †Department of Pediatrics, Children's Hospital of Pittsburgh; ‡Division of Pediatric Endocrinology, Department of Pediatrics, University of Pittsburgh School of Medicine; and §Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Insights
Myxedema coma, a rare condition in children, can present with altered mental status. This case highlights the importance of considering severe hypothyroidism in pediatric patients with hypoxemia and influenza.
Area of Science:
- Pediatric Endocrinology
- Critical Care Medicine
Background:
- Myxedema coma, a severe manifestation of hypothyroidism, is exceptionally rare in pediatric populations.
- Prompt diagnosis and management are crucial for favorable outcomes in pediatric critical care.
Observation:
- A 5-year-old girl presented with hypoxemia and altered mental status.
- The patient was diagnosed with severe hypothyroidism and myxedema coma.
- The condition occurred in the context of an acute influenza infection.
Findings:
- This case underscores the rarity of myxedema coma in childhood.
- Influenza infection can precipitate myxedema coma in susceptible pediatric patients.
- Severe hypothyroidism requires urgent recognition and intervention.
Implications:
- Myxedema coma should be included in the differential diagnosis for pediatric patients with altered mental status and organ dysfunction.
- Early identification of severe hypothyroidism is vital in pediatric emergency settings.
- This case emphasizes the need for heightened awareness of rare endocrine emergencies in children.
Abstract:
Childhood cases of myxedema coma are extremely rare. We report a case of a 5-year-old girl transferred to a tertiary care pediatric emergency department with hypoxemia and altered mental status and diagnosed with severe hypothyroidism and myxedema coma in the setting of acute influenza infection. Although it is rare, myxedema coma must remain in the differential diagnosis for altered mental status and organ dysfunction in the pediatric population.
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