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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Transient Transduction of the Strobilated Forms of Echinococcus granulosus
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Cystic pulmonary hydatidosis.

Malay Sarkar1, Rajnish Pathania2, Anupam Jhobta3

  • 1Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Lung India : Official Organ of Indian Chest Society
|April 7, 2016
PubMed
Summary

Cystic echinococcosis (CE) is a parasitic disease causing pulmonary hydatid cysts globally. This review covers CE pathogenesis, lifecycle, clinical features, and management, including surgery and benzimidazoles.

Keywords:
BenzimidazolesEchinococcus granulosuscystic echinococcosiswater-lily sign

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Area of Science:

  • Parasitology
  • Infectious Diseases
  • Public Health

Background:

  • Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by Echinococcus granulosus.
  • Pulmonary hydatid cysts represent a significant global health burden, impacting medical, social, and economic aspects.
  • Understanding the disease's lifecycle and transmission is crucial for control.

Purpose of the Study:

  • To provide a comprehensive overview of pulmonary hydatid disease.
  • To detail the pathogenesis, lifecycle, clinical manifestations, and management strategies for CE.
  • To consolidate current knowledge for clinicians and researchers.

Main Methods:

  • This is a review article, synthesizing existing literature.
  • Information was gathered from scientific databases and relevant publications.
  • Focus is on established knowledge regarding pathogenesis, lifecycle, clinical features, and treatment.

Main Results:

  • Pulmonary hydatidosis results from Echinococcus granulosus larval infection.
  • Clinical presentation varies, often asymptomatic until complications arise.
  • Surgical intervention is the primary treatment, with benzimidazoles as an alternative for specific cases.

Conclusions:

  • Pulmonary hydatid disease requires a thorough understanding of its multifaceted nature.
  • Effective management hinges on accurate diagnosis and appropriate therapeutic choices, including surgery or pharmacotherapy.
  • Continued research and public health initiatives are vital for controlling this zoonotic disease.