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Updated: Mar 23, 2026
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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
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Where does selective laser trabeculoplasty stand now? A review.
Myrjam De Keyser1, Maya De Belder2, Simon De Belder3
1Department of Medicine, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium ; Medipolis, Boomsesteenweg 223, B-2610 Antwerp, Belgium.
Eye and Vision (London, England)
|April 7, 2016
Summary
Selective laser trabeculoplasty (SLT) offers an effective alternative to daily eye drops for glaucoma management. Studies show SLT provides comparable results to medications and other laser treatments for lowering intraocular pressure.
Area of Science:
- Ophthalmology
- Glaucoma Management
- Laser Therapy
Background:
- Chronic glaucoma treatment adherence is challenging for some patients.
- Selective laser trabeculoplasty (SLT) is explored as a potential alternative to daily medication.
Purpose of the Study:
- To evaluate the efficacy of SLT as a primary or adjunctive therapy for glaucoma.
- To compare SLT outcomes with traditional glaucoma medications and argon laser trabeculoplasty (ALT).
Main Methods:
- Systematic review of randomized clinical trials (RCTs) comparing SLT with prostaglandin analogs and ALT.
- Analysis of eight RCTs and supplementary case reports on SLT side effects.
- Calculation of success rates from available trial data.
Main Results:
- SLT achieved a mean intraocular pressure (IOP) reduction of 3.8-8.0 mmHg within 6 months to 1 year.
- Mean SLT success rates ranged from 55-82% at 6 months to 1 year.
- Higher baseline IOP correlated with greater IOP reduction post-SLT.
Conclusions:
- SLT demonstrates efficacy as both a primary and adjunctive treatment for glaucoma.
- SLT shows no clinically relevant difference in IOP reduction, medication reduction, or success rates compared to prostaglandin analogs and ALT.
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