Related Experiment Video
Updated: Feb 10, 2026

Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes
Published on: June 25, 2017
Acute Glucose Response Properties Beyond Feeding
C Joseph Burnett1, Michael J Krashes2
1Diabetes, Endocrinology and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD, USA; National Institute on Drug Abuse (NIDA), National Institutes of Health, Baltimore, MD, USA; Brown-NIH Graduate Partnerships Program, Brown University, Providence, RI, USA.
Abstract:
Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.
Related Concept Videos
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Glucose Transporters
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Glucose Absorption Into the Small Intestine
Physical and Chemical Properties of Matter
Properties of Transition Metals
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...

