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Updated: Mar 23, 2026

Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
Physical activity in patients with anorexia nervosa
Najate Achamrah1, Moïse Coëffier2, Pierre Déchelotte2
1N. Achamrah is with the Department of Nutrition, Rouen University Hospital, Rouen, France. N. Achamrah and M. Coëffier are with the INSERM Unit 1073, University of Rouen, Rouen, France. P. Déchelotte is with the Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France. najate.achamrah@chu-rouen.fr.
Physical hyperactivity is common in anorexia nervosa (AN). While hyperactivity during refeeding can worsen outcomes, some physical activity may be safe and beneficial for AN patients, requiring personalized approaches.
Area of Science:
- Neuroscience
- Clinical Psychology
- Sports Medicine
Background:
- Anorexia nervosa (AN) frequently presents with physical hyperactivity.
- Neural pathway commonalities are suggested between AN and hyperactivity.
- Management of physical activity in AN treatment is debated.
Purpose of the Study:
- To review the role of hyperactivity in AN pathophysiology.
- To evaluate the impact of physical activity during AN refeeding.
- To propose guidelines for physical activity management in AN.
Main Methods:
- Literature review on hyperactivity in anorexia nervosa.
- Analysis of studies on physical activity during refeeding.
- Synthesis of current knowledge on AN treatment.
Main Results:
- Hyperactivity during refeeding correlates with increased energy needs, poorer outcomes, longer hospitalization, and higher psychiatric comorbidity.
- Preserving some physical activity during refeeding may aid body composition restoration, bone mineral density, and mood/anxiety management.
- Current guidelines for physical activity in AN are lacking.
Conclusions:
- Physical activity management during AN refeeding should be individualized based on patient status.
- Further research is needed to determine the benefits of programmed physical activity in AN treatment.
- Personalized physical activity may be a safe and beneficial component of AN care.
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