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Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice

Andrea N Edginton1, Eric I Zimmerman2, Aksana Vasilyeva2

  • 1School of Pharmacy, University of Waterloo, Waterloo, ON, Canada.

Cancer Chemotherapy and Pharmacology
|April 8, 2016
PubMed
Abstract

Keywords:
Efflux transportersInflux transportersPhysiologically based pharmacokineticsSensitivity analysisSorafenib

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