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Updated: Mar 23, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
A heart team and multi-modality imaging approach to percutaneous closure of a post-myocardial infarction ventricular
Sunil Iyer1, Thurston Bauer1, Michael Yeung1
1Departments of Cardiothoracic Surgery and Cardiology, University of North Carolina, Chapel Hill, NC 27599, USA.
Insights
Post-infarction ventricular septal defect (PI-VSD) is a severe complication. This study details a successful percutaneous closure using a multidisciplinary imaging approach for select patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Post-infarction ventricular septal defect (PI-VSD) is a rare but serious complication of myocardial infarction.
- High mortality rates are associated with both surgical repair and conservative management of PI-VSD.
- Percutaneous closure offers a less invasive alternative for carefully selected patients.
Observation:
- A multidisciplinary team utilized a multi-modality imaging approach to characterize the PI-VSD.
- Detailed imaging was crucial for appropriate patient and device selection.
- The approach facilitated the planning and execution of the percutaneous closure procedure.
Findings:
- Successful percutaneous closure of a post-infarction ventricular septal defect was achieved.
- The integrated imaging strategy enabled precise anatomical assessment and device deployment.
- The patient's outcome following the procedure was positive.
Implications:
- This case highlights the feasibility and effectiveness of percutaneous closure for PI-VSD in select individuals.
- A multidisciplinary, imaging-guided approach is essential for optimizing outcomes in complex structural heart interventions.
- This strategy may expand treatment options for patients with PI-VSD, potentially reducing morbidity and mortality.
Abstract:
Post-infarction ventricular septal defect (PI-VSD) is a devastating complication that carries a high mortality with or without surgical repair. Percutaneous closure is an attractive alternative in select patients though requires appropriate characterization of the PI-VSD as well as careful device and patient selection. We describe a multidisciplinary and multi-modality imaging approach to successful percutaneous closure of a PI-VSD.

